RICERCA SCIENTIFICA OMEOPATICA

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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio nov 08, 2012 2:45 am

A controlled clinical trial for testing the efficacy of the homeopathic drug eupatorium perfoliatum D2 inthe treatment of common cold

Abstract
53 outpatients suffering from common cold (flu) were randomly assigned to either a therapy with acetylsalicylic acid (ASA) or the homeopathic drug Eupatorium perfoliatum D2 in a controlled clinical trial. The efficacy of the drugs was assessed on day 1, 4 and 10 of the infection by symptom check lists and physical examinations. Neither subjective complaints nor body temperature or laboratory findings showed any significant differences between groups which was taken as evidence that both drugs were equally effective.

Fonte:
Arzneimittelforschung. 1981;31(4):732-6.
http://www.ncbi.nlm.nih.gov/pubmed/7195723
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio nov 08, 2012 2:48 am

Salicylates and homoeopathy in rheumatoid arthritis: preliminary observations.

Abstract

This paper reports the results of a pilot study in which 41 patients with rheumatoid arthritis were treated with high doses of salicylate, 3.9 g per day, and the results compared with a further 54 similar patients treated with homoeopathy. Both groups were compared with 100 patients who received placebo. 2 The patients who received homoeopathy did better than those who received salicylate. The design of the trial was such, however, that it was not possible to distinguish between the effects due to the physicians and the effects due to the drugs and a further trial is planned to elucidate this point. 3 Patients on homoeopathic treatment did not experience toxic effects.

Fonte:
Br J Clin Pharmacol. 1978 November; 6(5): 391–395.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1429555/
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio nov 08, 2012 2:50 am

Homoeopathic therapy in rheumatoid arthritis: evaluation by double-blind clinical therapeutic trial.

Abstract

Twenty-three patients with rheumatoid arthritis on orthodox first-line anti-inflammatory treatment plus homeopathy were compared wtih a similar group of twenty-three patients on orthodox first-line treatment plus an inert preparation. There was a significant improvement in subjective pain, articular index, stiffness and grip strength in those patients receiving homoeopathic remedies whereas there was no significant change in the patients who received placebo. Two physicians were involved in prescribing for the patients and there were no significant differences in the results which they obtained. No side effects were observed with the homoeopathic remedies.

Fonte
Br J Clin Pharmacol. 1980 May; 9(5): 453–459.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1429952/
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio nov 08, 2012 2:54 am

Measuring the Effects of Acupuncture and Homeopathy in General Practice: An Uncontrolled Prospective

Abstract
Background
Despite the increasing demand for acupuncture and homoeopathy in Germany, little is known about the effects of these treatments in routine care. We set up a pragmatic documentation study in general practice funded within the scope of project launched by a German health insurer. Patients were followed-up for up to four years.

Methods
The aim of the project was to study the effects and benefits of acupuncture and/or homoeopathy, and to assess patient satisfaction within a prospective documentation of over 5000 acupuncture and over 900 homoeopathy patients. As data sources, we used the documentation made available by therapists on every individual visit and a standardised quality-of-life questionnaire (MOS SF-36); these were complemented by questions concerning the patient's medical history and by questions on patient satisfaction. The health insurer provided us with data on work absenteeism.

Results
Descriptive analyses of the main outcomes showed benefit of treatment with middle to large-sized effects for the quality of life questionnaire SF-36 and about 1 point improvement on a rating scale of effects, given by doctors. Data on the treatment and the patients' and physicians' background suggests chronically ill patients treated by fairly regular schemes.

Conclusion
Since the results showed evidence of a subjective benefit for patients from acupuncture and homoeopathy, this may account for the increase in demand for these treatments especially when patients are chronically ill and unsatisfied with the conventional treatment given previously.

Fonte:
Guthlin C., Lange O., Walach H. Measuring the Effects of Acupuncture and Homeopathy in General Practice: An Uncontrolled Prospective Documentation Approach. Biomed Central Public Health, 2004, 4, 1, 6. 5000
http://www.biomedcentral.com/1471-2458/4/6
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio nov 08, 2012 2:58 am

A placebo controlled clinical trial investigating the efficacy of a homeopathic after-bite gel in reducing mosquito bite induced erythema.

Abstract
A randomised, placebo controlled clinical trial was conducted to examine the efficacy of a homeopathic after-bite gel in the symptomatic relief of mosquito bites. Sixty eight healthy volunteers were bitten under laboratory conditions by Aedes aegypti mosquitoes at three spots, on the ventral aspect of the forearm. One bite was treated with the homeopathic after-bite gel, another bite with a placebo gel which was identical in appearance and smell to the homeopathic after-bite gel, and the third bite remained untreated. Immediately after the bites and 1, 3, 6, 26 and 31 hours post-bite, the length and width of the erythema were measured with a calliper, and photographs were taken of the bite sites from which the size of the erythema was subsequently determined. This was followed by assessment of the extent of itching with a verbal analogue scale, and finally treatment took place. For each spot the total erythema was calculated as the area under the plotted curve of the erythema at different time points (mm2*h) and the total sum of the itch scores was determined. For the bites treated with the homeopathic after-bite gel the median total erythema was 10.500 mm2*h. For the spots treated with the placebo gel and the untreated spots the median total erythema was 12.900 mm2*h and 13.300 mm2*h, respectively. The difference between the spots treated with the homeopathic after-bite gel and the untreated spots came close to significance (two-tailed P = 0.06), which was not the case for the difference between the spots treated with the homeopathic after-bite gel and the spots treated with placebo gel (P = 0.13). After pooling the data of a very similar previous pilot study and the present study (ntotal = 83), the homeopathic after-bite gel was significantly superior to no treatment (two-tailed P = 0.003) as well as to placebo gel (two-tailed P = 0.03). Comparing itching after the three treatments, no significant differences could be demonstrated. The extent of itching was positively correlated with the area of the erythema (r = 0.63). Treatment of mosquito bites with the homeopathic after-bite gel will reduce the erythema compared to no treatment. Comparison with the placebo gel suggests it is the plant extracts which are the active components of this gel.

Fonte:
Eur J Clin Pharmacol. 1995;49(1-2):103-8.
http://www.ncbi.nlm.nih.gov/pubmed/8751030
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio nov 08, 2012 3:03 am

Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial.

Abstract
BACKGROUND:
The use of antibiotics in the initial treatment of acute otitis media is currently being questioned. Homeopathy has been used historically to treat this illness, but there have been no methodologically rigorous trials to determine whether there is a positive treatment effect.
METHODS:
A randomized double blind placebo control pilot study was conducted in a private pediatric practice in Seattle, WA. Seventy-five children ages 18 months to 6 years with middle ear effusion and ear pain and/or fever for no more than 36 h were entered into the study. Children received either an individualized homeopathic medicine or a placebo administered orally three times daily for 5 days, or until symptoms subsided, whichever occurred first. Outcome measures included the number of treatment failures after 5 days, 2 weeks and 6 weeks. Diary symptom scores during the first 3 days and middle ear effusion at 2 and 6 weeks after treatment were also evaluated.
RESULTS:
There were fewer treatment failures in the group receiving homeopathy after 5 days, 2 weeks and 6 weeks, with differences of 11.4, 18.4 and 19.9%, respectively, but these differences were not statistically significant. Diary scores showed a significant decrease in symptoms at 24 and 64 h after treatment in favor of homeopathy (P < 0.05). Sample size calculations indicate that 243 children in each of 2 groups would be needed for significant results, based on 5-day failure rates.
CONCLUSIONS:
These results suggest that a positive treatment effect of homeopathy when compared with placebo in acute otitis media cannot be excluded and that a larger study is justified.

http://www.ncbi.nlm.nih.gov/pubmed/11224838
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio nov 08, 2012 3:06 am

Homeopathy for childhood diarrhea: combined results and metaanalysis from three randomized, controlled clinical trials.

Abstract
BACKGROUND:
Previous studies have shown a positive treatment effect of individualized homeopathic treatment for acute childhood diarrhea, but sample sizes were small and results were just at or near the level of statistical significance. Because all three studies followed the same basic study design, the combined data from these three studies were analyzed to obtain greater statistical power.
METHODS:
Three double blind clinical trials of diarrhea in 242 children ages 6 months to 5 years were analyzed as 1 group. Children were randomized to receive either an individualized homeopathic medicine or placebo to be taken as a single dose after each unformed stool for 5 days. Parents recorded daily stools on diary cards, and health workers made home visits daily to monitor children. The duration of diarrhea was defined as the time until there were less than 3 unformed stools per day for 2 consecutive days. A metaanalysis of the effect-size difference of the three studies was also conducted.
RESULTS:
Combined analysis shows a duration of diarrhea of 3.3 days in the homeopathy group compared with 4.1 in the placebo group (P = 0.008). The metaanalysis shows a consistent effect-size difference of approximately 0.66 day (P = 0.008).
CONCLUSIONS:
The results from these studies confirm that individualized homeopathic treatment decreases the duration of acute childhood diarrhea and suggest that larger sample sizes be used in future homeopathic research to ensure adequate statistical power. Homeopathy should be considered for use as an adjunct to oral rehydration for this illness.

Fonte:
http://www.ncbi.nlm.nih.gov/pubmed/12634583
Pediatr Infect Dis J. 2003 Mar;22(3):229-34.
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il lun dic 10, 2012 1:30 pm

Efficacia di Oscillococcinum per il trattamento dell'influenza

The use of a complementary medicine approach, and specifically of the popular medicine Oscillococcinum, for the treatment of influenza-like syndromes remains controversial. This brief paper analyses the currently available literature on this homeopathic preparation and the Cochrane Collaboration's 2006 systematic review, along with other recent studies, in order to clarify certain fundamental aspects of its use in the treatment of influenza. In the light of the reported findings, and applying the rigorous criteria of evidence-based medicine, we suggest that this medicine should be placed in category "BI".

Fonte:
Ann Ist Super Sanita. 2012;48(1):105-9.
http://www.ncbi.nlm.nih.gov/pubmed/22456024
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio feb 13, 2014 11:14 am

Con l'omeopatia il mais germina meglio

di Carlo Di Stanislao

Un problema che riguarda da sempre il mondo agrario è rappresentato dalla scarsa capacità di mantenere nel tempo una buona possibilità germinativa da parte del seme di mais. In un lavoro effettuato dal gruppo di Vesna Dragicevic, preparazioni omeopatiche alla 2DH e 4DH dello stesso germe si sono dimostrate in grado di indurre una persistenza del potenziale germinativo nel tempo. A tale scopo è stato allestito un modello sperimentale con semi di quattro linee di mais, sottoposti ad un trattamento che ha prodotto un invecchiamento accelerato mentre una parte di semi sono stati sottoposti ad azione di acqua distillata con dinamizzazioni diverse (DH2, DH4, CH3, CH3,75, CH4,5 CH5,25 e CH6) di germe di grano.
Rispetto ai controlli non trattarti, i semi invecchiati e trattati poi con acqua e preparati omeopatici hanno dimostrato maggiore capacità germinativa, calcolata valutando diversi parametri: quantità di sostanza fresca, lunghezza della radice, misurazione della capacita di idrolisi e biosintesi, funzione redox. Tutte le dinamizzazioni, ma soprattutto la DH2 e la DH4, hanno mostrato un valore statisticamente migliore su questi parametri rispetto ai controlli. Per quanto riguarda la funzione di crescita e redox, anche le potenze CH3 e CH4,5 sembrano risultare statisticamente significative, senza però grande influenza sugli altri valori.

Homeopathy, 2013, 102, (3), 179

Per leggere l'abstract : http://www.siomi.it/apps/pubblicazioni.php?id=1282

Fonte:
Omeopatia33, 13 febbraio 2014 - Anno 9, Numero 3
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Re: RICERCA SCIENTIFICA OMEOPATICA

Messaggiodi Dr.Ascani il gio feb 13, 2014 11:16 am

Un trial clinico con un nosode dell'Epatite C

di Tiziana Di Giampietro

Con l'obiettivo di introdurre il nuovo nosode dell'epatite C nella farmacopea omeopatica, Rajesh Shah e altri ricercatori, hanno condotto uno studio in doppio cieco, randomizzato e controllato con placebo, preparato con un metodo riproducibile e standardizzabile, per ricavarne dati sperimentali. Il farmaco usato nel trial nasce dalla collaborazione e approvazione di un team di virologi immunologi, biotecnologi, omeopati, farmacologi ed epatologi.
Nello studio, che ha avuto l'approvazione del Comitato Etico, sono stati arruolati 22 volontari, addestrati a redigere un diario delle modalità dei sintomi emersi dopo l'assunzione, una volta alla settimana per 4 settimane, di una preparazione del medicinale. Di questi, 15 hanno ricevuto Hepatite 30CH (nosode di Epatite C, genotipo I e III), 7 hanno ricevuto il placebo. Dai dati analizzati è emerso che Hepatite 30CH ha evocato sintomi quali e quantitativamente definiti, significativamente più importanti di quelli indotti dal placebo e corrispondenti a quelli provocati dalla malattia, dunque utili per elaborare la patogenesi del medicinale. In conclusione lo studio ha dimostrato una più alta incidenza di effetti patogenetici nei volontari trattati in verum (9) rispetto a quelli con placebo (4,28), elemento che sostiene la tesi di Walach et al. 2009, secondo i quali i medicinali omeopatici producono effetti diversi dal placebo. Questi risultati dovrebbero essere convalidati, anche in considerazione dell'utilità che il nosode dell'Epatite C potrebbe avere nel trattamento di malattie immunologicamente mediate come l'epatite cronica (infettiva, alcolica, non infettiva), il cancro epatico e le patologie correlate.

Homeopathy, 2013, 102, (3), 207
http://www.siomi.it/apps/pubblicazioni.php?id=1286

Fonte:
Omeopatia33, 13 febbraio 2014 - Anno 9, Numero 3
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